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Fluvastatin；氟伐他汀Canef|||XU-62320|||Vastin|||Cranoc|||Lescol；Canef|||XU-62320|||Vastin|||Cranoc|||Les (2024/9/2)
簡介：fluvastatin (xu-62320) is a potent and competitive hmg-coa reductase inhibitor (ic50: 8 nm) that inhibits oxidative stress in vascular smooth muscle cells through an nrf2-dependent pathway, and is used for the reduction of plasma cholesterol levels and the prevention of cardiovascular disease.
Fluticasone furoate；糠酸氟替卡松Veramyst|||Allermist|||Avamys|||Fluticasone furoate；Veramyst|||Allermist|| (2024/9/2)
簡介：fluticasone furoate (avamys) is a synthetic trifluorinated corticosteroid derived from fluticasone with a kd of 0.3 nm. fluticasone furoate has potent anti-inflammatory, anti-asthmatic activity, and low systemic exposure. fluticasone furoate can be used as a nasal spray for studies about allergic rhinitis treatment.
Flupenthixol；化合物 T21401Siplaril|||Depixol|||Fluanxol|||Emergil；Siplaril|||Depixol|||Fluanxol|||Emerg (2024/9/2)
簡介：flupentixol is a typical antipsychotic drug of the thioxanthene class. flupentixol is also used in low doses as an antidepressant.
Cefotetan disodium；化合物 T21400YM09330|||YM-09330|||ICI-156834|||ICI 156834|||YM 09330|||Cefotetan Sod (2024/9/2)
簡介：cefotetan sodium, a second-generation cephalosporin, cephamycin antibiotic, is active against a wide range of both aerobic and anaerobic gram-negative and gram-positive bacteria. cefotetan disrupts the cell wall synthesis by binding to penicillin-binding proteins.
Parthenolide；小白菊內(nèi)酯(-)-Parthenolide；(-)-Parthenolide|||小白菊內(nèi)酯 (2024/9/2)
簡介：(-)-parthenolide ((-)-parthenolide), an inhibitor of the nuclear factor-κb pathway, also promotes the ubiquitination of mdm2 and activates p53 cellular functions.
Butacaine sulfate；化合物 T2139LButyn|||AI3 02405|||AI302405|||AI3-02405；Butyn|||AI3 02405|||AI302405||| (2024/9/2)
簡介：butacaine sulfate is applied to mucous membranes as a local anesthetic.
Luseogliflozin；化合物 T21399TS71|||TS-071|||TS 71|||TS071|||TS-71|||TS 071；TS71|||TS-071|||TS 71|||TS07 (2024/9/2)
簡介：luseogliflozin, a potent and competitive inhibitor of sodium-dependent glucose cotransporter 2 (sglt2), competitively inhibits human sglt2-mediated glucose uptake with a ki value of 1.10 nm.
Tiazotic acid；化合物 T21398Tiazotic acid (2024/9/2)
簡介：tiazotic acid is an agent with the activity of antioxidant.
Finerenone；化合物FinerenoneBAY948862|||BAY-948862|||BAY94-8862|||BAY 94-8862|||BAY-94-8862|||BAY 948862 (2024/9/2)
簡介：finerenone (bay-948862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (mr) antagonist with ic50 of 18 nm for the treatment of chronic heart failure. finerenone (bay-948862) displays excellent selectivity versus glucocorticoid receptor (gr), androgen receptor (ar), and progesterone receptor (>500-fold).
Sarecycline hydrochloride；化合物 T21394P005672|||P-005672|||WC-3035|||WC 3035|||Sarecycline HCl|||WC303 (2024/9/2)
簡介：sarecycline, a novel and tetracycline-derived antibiotic, is being developed for use as an oral once daily antibiotic treatment for patients suffering from moderate to severe acne vulgaris. sarecycline has anti-inflammatory activity and the potential for a favorable tolerability profile.
Ethopropazine Hydrochloride；化合物 T21393Lysivane|||Parphezein|||Dibutil|||Parfezin|||Profenamine HCl|| (2024/9/2)
簡介：ethoproprazine hydrochloride is an butyrylcholinesterase inhibitor. it reduces extrapyramidal motor effects and used as an antidyskinetic, characteristic of parkinson′s disease. it also alleviates thermal hyperalgesia in rats.
Flunarizine；化合物 T21392Flunarizinum|||Flunarizin|||Sibelium|||Flunarizina|||R-14950；Flunarizinum|||Fl (2024/9/2)
簡介：flunarizine is a non-selective calcium entry blocker and a histamine h1 receptor blocker. it is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Flecainide；化合物 T21391Tambocor|||Apocard|||Flecainida|||Flecainidum；Tambocor|||Apocard|||Flecainida|| (2024/9/2)
簡介：flecainide acetate is a class ic antiarrhythmic agent, it is used to treat a variety of cardiac arrhythmias including paroxysmal atrial fibrillation, paroxysmal supraventricular tachycardia, and ventricular tachycardia. it works by regulating the flow of sodium in the heart, causing prolongation of the cardiac action potential.
Fexofenadine；非索非那定Carboxyterfenadine|||Telfast|||MDL 16.455|||Allegra；Carboxyterfenadine|||Telfast|| (2024/9/2)
簡介：fexofenadine (carboxyterfenadine), an antihistamine pharmaceutical drug, is used to treat allergy symptoms, such as nasal congestion, hay fever, and urticaria. compared to first-generation antihistamines, fexofenadine is less able to pass the blood-brain barrier and cause sedation.
Oxyphencyclimine；化合物 T2138LOxiphencycliminum|||Antulcus|||Zamanil|||Manir|||Caridan|||Naridan；Oxiphe (2024/9/2)
簡介：oxyphencyclimine is a muscarinic receptor antagonist (mra) anticholinergic drug used to treat peptic ulcers.
Enprofylline；恩丙茶堿Enprofilina|||3-propylxanthine|||3-n-Propylxanthine|||Enprofyllinum；Enprofilina|||3 (2024/9/2)
簡介：enprofylline (enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor. enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of sickle cell disease, diabetic neuropathy, and cerebrovascular insufficiency.
Emedastine Difumarate富馬酸依美斯汀Rapimine|||DSSTox_CID_26911|||AL-3432A|||富馬酸依美斯汀|||KB-2413|||Emedastine (2024/9/2)
簡介：emedastine difumarate is a selective histamine h1 receptor antagonist with anti-allergic activity, prescribed for allergic conjunctivitis. upon ocular administration, emedastine causes a dose-dependent inhibition of histamine-stimulated vascular permeability in the conjunctiva.
Nafoxidine；萘福昔定Nafoxidine (2024/9/2)
簡介：nafoxidine is an estrogen antagonist that has been used in the treatment of breast cancer.
Nafoxidine HCl（1845-11-0 Free base）；化合物Nafoxidine HCl（1845-11-0 Free base）PNU-0011100|||PNU0011100|| (2024/9/2)
簡介：nafoxidine is a partial estrogen antagonist. it inhibits angiogenesis in some tissues by blocking the effects of vegf and fgf; paradoxically, it may enhance angiogenesis in uterine tissue. nafoxidine also induces calcium signaling, oxidative stress, and protein kinase c.
Ceftizoxime Sodium；頭孢唑肟鈉Epocelin|||Eposerin|||Monosodium Salt, Ceftizoxime|||Cefizox|||Ceftizoxime s (2024/9/2)
簡介：ceftizoxime, a third-generation cephalosporin effective against gram-negative and gram-positive bacteria, binds penicillin-binding proteins (pbps) to inhibit the bacterial cell wall synthesis. it rather resembles cefotaxime in its properties but is not subject to metabolism.
Cinitapride；西尼必利Paxapride|||Cidine|||cinitapride tartrate|||Blaston|||Cintapro|||Cinmove；西尼必利|||Paxa (2024/9/2)
簡介：cinitapride (blaston) is a gastroprokinetic agent. it slows the actions of the muscles to reduce the symptoms of conditions such as acid reflux, delayed gastric emptying, and ulcer dyspepsia. cinitapride acts as an antagonist of the 5-ht2 receptors and as an agonist of the 5-ht1 and 5-ht4 receptors.
Dicloxacillin；化合物 T21384Dicloxacilina|||Dicloxacycline|||Dicloxacillinum|||Dicloxacilline|||Diclocil (2024/9/2)
簡介：dicloxacillin (inn), a narrow-spectrum β-lactam antibiotic of the penicillin class, is used against beta-lactamase-producing organisms such as staphylococcus aureus, which would otherwise be resistant to most penicillins.
Dextrothyroxine sodium；化合物 T21383LDextrotiroxina sodica|||Lisolipin|||D-T4 sodium；Dextrotiroxina sod (2024/9/2)
簡介：dextrothyroxine sodium is the dextrorotary isomer of thyroxine.
D-Thyroxine；D-甲狀腺素Dethyrona|||Detyroxin|||Dextroid|||Dextrothyroxine;Biotirmone|||Dextroxin|||Biotir (2024/9/2)
簡介：d-thyroxine (dextroxin) could lower cholesterol and also increases hepatic lipase which in turn improves utilization of triglycerides, leading to improve apolipoprotein e cholesterol particles.
Dapiprazole；化合物 T21381Dapiprazol|||Glamidolo|||Reversil；Dapiprazol|||Glamidolo|||Reversil (2024/9/2)
簡介：dapiprazole, an alpha blocker, is used to reverse mydriasis after eye examination.
Oxyphencyclimine Hydrochloride鹽酸奧克西利平鹽酸奧克西利平|||Spazamin|||Daricon|||Ulcociclinina (2024/9/2)
簡介：oxyphencyclimine hydrochloride (ulcociclinina) is a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities.
Aloisine A；化合物 T21377Aloisine A (2024/9/2)
簡介：aloisine a is a potent and selective cdk/gsk-3 inhibitor. ic50 data of aloisine a: cdk1/cyclin b (ic50: 150nm), cdk2/cyclin a (ic50: 120nm), cdk2/cyclin e (ic50: 400nm), cdk5/p25 (ic50: 200nm), cdk5/p35 (ic50: 160nm), gsk-3α (ic50: 500nm), gsk-3β (ic50: 650nm), jnk (ic50~3-10μm).
Chlorphenesin Carbamate；氯苯氨酸甘油酯Kolpicortin-sine|||Rinlaxer|||Chlorphensin carbamate|||Maolate|||laCh (2024/9/2)
簡介：chlorphenesin carbamate is a centrally acting muscle relaxant used to treat muscle pain and spasms and also an antifungal agent.
Clocortolone；化合物 T21374Clocortolona|||Clocortolonum|||Cloderm；Clocortolona|||Clocortolonum|||Cloderm (2024/9/2)
簡介：clocortolone is a corticosteroid hormone receptor agonist. it is used in the form of an ester, clocortolone pivalate, and applied as a cream. clocortolone pivalate is used to treat dermatitis and is considered a medium-strength corticosteroid.
Aprindine hydrochloride；化合物 T21373Fiboran|||Amidonal|||Aprinidine|||Aprindin|||Aprindine HCl|||Aprin (2024/9/2)
簡介：aprindine hcl is a class 1b antiarrhythmic agent used to manage ventricular and supraventricular arrhythmias. in one study, it delayed atrial fibrillation more than digoxin did. it has shown effectiveness when given orally.
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